Vitamin E may help prevent cancer

April 1, 2004 in Cancer Prevention, Nutrition Topics in the News, Vitamins, Minerals, Supplements

Vitamin E may help prevent cancer

Vitamin E protects against at least two common forms of cancer - prostate and bladder - but popping supplements is probably not the best way to get the vital nutrient, researchers said last week. Two studies found that people who either ate the most vitamin E-containing food or who had the highest levels in the blood were the least likely to have cancer.

But the researchers also noted that there are several different forms of vitamin E and the kind you eat (alpha tocopherol) is key. And the best-absorbed form of alpha tocopherol is not found in supplements but in foods such as sunflower seeds, spinach, almonds and sweet peppers.

In one of the studies presented to the annual meeting of the American Association of Cancer Research in Orlando, researchers from the U.S. National Cancer Institute found men with the most vitamin E in their systems had the lowest risk of prostate cancer.

They looked at data from 29,133 Finnish men aged between 50 and 69 taking part in a smokers' study. All gave blood at the beginning of the study and then took vitamins to see whether the supplements might prevent various forms of cancer. This study is best known for showing that smokers who took beta carotene (which the body converts to vitamin A) actually had higher rates of lung cancer.

The researchers looked at vitamin E and prostate cancer, and at how much E the men had in their blood before they ever took a supplement. The men who had higher serum (blood) levels of vitamin E had a lower chance of getting prostate cancer.

Then they looked at the two main forms of vitamin E - alpha tocopherol and gamma tocopherol. Men with the highest natural levels of alpha tocopherol were 53% less likely to later develop prostate cancer. Men with the highest levels of gamma tocopherol, which only represents about 20% of the vitamin E in blood - had a 39% lower chance. Taking supplements further reduced prostate cancer rates.

Nuts and seeds, whole grain products, vegetable oils, salad dressings, margarine, beans, peas and other vegetables are good dietary sources of vitamin E.

Researchers asked 1,000 volunteers what they ate, and estimated how much alpha-tocopherol and how much gamma tocopherol they got in their everyday diets and from supplements if they took them. Those with the highest intake of alpha tocopherol from food had a 42% reduced risk of bladder cancer, and those who had a vitamin E-rich diet and took supplements too had a 44% lower risk. But when broken down into types, they found gamma tocopherol offered no protection against bladder cancer.

Many vitamin E supplements, the researchers said, contain both active and inactive forms of the vitamin and may not be the best source. Sunflower seeds are high in selenium, another key nutrient, while greens are loaded with desirable nutrients.

All research on this web site is the property of Leslie Beck Nutrition Consulting Inc. and is protected by copyright. Keep in mind that research on these matters continues daily and is subject to change. The information presented is not intended as a substitute for medical treatment. It is intended to provide ongoing support of your healthy lifestyle practices.