Researchers report in the Archives of Neurology that supplements of omega-3 fatty acids may slow the mental decline in people with very mild Alzheimer's disease, but have no impact on people with more advanced forms of the disease.
This is the first randomized, double-blind, placebo-controlled study of its kind to be published on the effects of omega-3 fatty acid supplementationResearchers recruited 204 patients with varying degrees of Alzheimer's disease, 174 patientscompleted the year-long study. . were initially assigned to ether the omega-3 supplemented group (daily intake of 1720 mg DHA, 600 mg EPA) or a placebo (corn oil with 0.6 g linoleic acid).
After six months the omega-3 supplemented group showed 2.4 and 3.6-fold increases in the serum ratios of DHA and EPA, respectively. Both groups were then assigned to receive the omega-3 supplements for a further six months. Cognitive function was then assessed.
After 12 months both groups (omega-3/omega-3 and placebo/omega-3) had similar blood levels of DHA and EPA levels. However, when the researchers looked at a subset of patients with very mild Alzheimer's (32 patients), a statistically significant effect was observed.
Further studies are needed to examine the mechanism by which omage-3s may offer protection against mild Alzheimer's.
All research on this web site is the property of Leslie Beck Nutrition Consulting Inc. and is protected by copyright. Keep in mind that research on these matters continues daily and is subject to change. The information presented is not intended as a substitute for medical treatment. It is intended to provide ongoing support of your healthy lifestyle practices.